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PLOS Science Wednesday: Hi reddit, I'm Ole Andreassen and my colleagues and I developed and vali

View the entire Ask Me Anything (AMA) here. Highlights: Hi Reddit,My name is Ole Andreassen and I am a Professor in Psychiatry at University of Oslo. I have also a clinical position where I see patients regularly in the outpatient clinic at Oslo University Hospital. My research focuses on severe mental illness and neurodegenerative diseases.We recently published an article titled Genetic assessment of age-associated Alzheimer’s disease risk: development and validation of a polygenic hazard score in PLOS Medicine. In this paper, we describe the development and validation of a new genetic score to predict Alzheimer's disease age of onset. Our results show that genetic data can be combined wi

What do we think of glucosamine/chondroitin supplements?

Due to the unregulated supplement market, and concerns that the the quality of store-bought supplements is highly suspect, we typically will not recommend our patients take glucosamine/chondroitin supplements, unless it is from a third-party certified lab (such as Thorne Research), and even then, the research doesn't support benefit. Ultimately, you must check the source of your supplements - do they have 3rd party assessment? Robert H. Shmerling, MD, Faculty Editor, from Harvard Health Publications, discussed this topic and reported that, "in a 2010 analysis of multiple studies (called a meta-analysis) found that among more than 3,800 people with osteoarthritis of the knee or hip, treatmen

Misusing antibiotics? Needing a safe, effective alternative? Consider Chinese Herbal Medicine.

So I was reading a Medscape article about the inappropriate use of antibiotics, particularly in cases of pneumonia occurring in children. The article is titled 'Inappropriate Antibiotic Use for Pneumonia Common' and reviews recent research showing that doctors continue to inappropriately prescribe antibiotics for cases of pneumonia. From the article: "Inappropriate prescribing of antibiotics is a persistent problem in medicine, despite known harms, Dr Hersh and Dr Kronman explain. In some cases, physicians choose to prescribe antibiotics for conditions, such as viral infections, for which they provide little benefit. In fact, 30% of all antibiotics prescribed to outpatients fall into this

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